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Carcinogenesis In a very lifetime carcinogenicity analyze completed in B6C3F1 mice, methylphenidate induced a rise in hepatocellular adenomas, and in males only, an increase in hepatoblastomas in a each day dose of somewhere around 60 mg/kg/day. This dose is around two moments the MRHD of 60 mg/working day offered to small children on mg/m2 foundat